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authFullName_s : Sophie Desmots

Identification of genes regulated by the environmental contaminant benzo(a)pyrene in primary human macrophages

Lydie Sparfel , Marie-Laure Pinel-Marie , Magali Boize , Serge Koscielny , Sophie Desmots , et al.
Annual Meeting 100th American Association for Cancer Research, Apr 2009, Denver, United States
Conference papers hal-00673940v1

AhR-dependent induction of the NADPH oxidase component p47phox by benzo(a)pyrene in human macrophages

Marie-Laure Pinel-Marie , Lydie Sparfel , Sophie Desmots , Olivier Fardel
Annual Meeting 100th American Association for Cancer Research, Apr 2009, Denver, United States
Conference papers hal-00674272v1

Perturbateurs de la fonction endocrinienne et santé : un point non exhaustif sur les connaissances

Sophie Desmots , Catherine Brulez , Emmanuel Lemazurier
Environnement, Risques & Santé, 2005, 4 (3), pp.195-204
Journal articles ineris-00962957v1
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Predicting in vivo gene expression in macrophages after exposure to benzo(a)pyrene based on in vitro assays and toxicokinetic/toxicodynamic models

Alexandre R.R. Pery , Céline Brochot , Sophie Desmots , Magali Boize , Lydie Sparfel , et al.
Toxicology Letters, 2011, 201 (1), pp.8-14. ⟨10.1016/j.toxlet.2010.11.017⟩
Journal articles hal-00873317v1

Modulation de la localisation cellulaire de la claudine 11 et de la p-glycoprotéine durant le développement postnatal chez le rat : mise en évidence d'un nouveau concept d'auto-défense du testicule immature et implication dans la barrière hémato-testiculaire

Audrey Legendre , Sophie Desmots , Anthony Lecomte , Franck Robidel , Olivier Dupont , et al.
Congrès de la SPTC. Sociétés de Pharmacologie-Toxicologie Cellulaire "Toxicologie Prédictive : les Voies du Futur", May 2010, Paris, France
Conference papers ineris-00970621v1

The in vitro blood-testis-barrier : a new promising alternative for reproductive toxicity studies

Audrey Legendre , Sophie Desmots , Anthony Lecomte , Pascal Froment , René Habert , et al.
2. International Conference on Innovation for Sustainable Production 2010 (I-SUP2010), May 2010, Bruges, Belgium
Conference papers ineris-00970639v1

Effects of endocrine disruptors on steroidogenic enzymes gene expression and on aromatase activity in two human cell lines

Nadia Quignot , Sophie Desmots , Robert Barouki , Emmanuel Lemazurier
92. Annual Meeting & Expo (ENDO 2010), Jun 2010, San Diego, United States
Conference papers ineris-00970646v1
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Evaluation of Placental Transfer and Tissue Distribution of cis- and Trans-Permethrin in Pregnant Rats and Fetuses Using a Physiological-Based Pharmacokinetic Model

Stéphane Personne , Céline Brochot , Paulo Marcelo , Aurélie Corona , Sophie Desmots , et al.
Frontiers in Pediatrics, 2021, 9, ⟨10.3389/fped.2021.730383⟩
Journal articles ineris-03498668v1
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An engineered 3D blood-testis barrier model for the assessment of reproductive toxicity potential

Audrey Legendre , Pascal Froment , Sophie Desmots , Anthony Lecomte , René Habert , et al.
Biomaterials, 2010, 31 (16), pp.4492-4505. ⟨10.1016/j.biomaterials.2010.02.029⟩
Journal articles istex ineris-00963581v1
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PBPK modeling of the cis- and trans-permethrin isomers and their major urinary metabolites in rats

Marie-Emilie Willemin , Sophie Desmots , Rozenn Le Grand , François Lestremau , Florence Anna Zeman , et al.
Toxicology and Applied Pharmacology, 2016, 294, pp.65-77. ⟨10.1016/j.taap.2016.01.011⟩
Journal articles ineris-01862928v1
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Substance-tailored testing strategies in toxicology : an in silico methodology based on QSAR modeling of toxicological thresholds and Monte Carlo simulations of toxicological testing

Alexandre R.R. Pery , Sophie Desmots , Enrico Mombelli
Regulatory Toxicology and Pharmacology, 2010, 56 (1), pp.82-92. ⟨10.1016/j.yrtph.2009.09.009⟩
Journal articles ineris-00961749v1

L'évaluation des risques liés à une exposition aux Hydrocarbures Aromatiques Polycycliques (HAPs) : nouvelle approche

Magali Boize , Alexandre R.R. Pery , Sophie Desmots , Serge Koscielny , Lydie Sparfel , et al.
Colloque International francophone "Les hydrocarbures aromatiques polycycliques, de la recherche à la prévention", Sep 2008, Montréal, Canada
Conference papers ineris-00970373v1

Développement d'un modèle de barrière hemato-testiculaire (BHT) in vitro pour l'évaluation des reprotoxiques

Audrey Legendre , Sophie Desmots , Anthony Lecomte , Pascal Froment , René Habert , et al.
Congrès de la SPTC. Sociétés de Pharmacologie-Toxicologie Cellulaire "Toxicologie Prédictive : les Voies du Futur", May 2010, Paris, France
Conference papers ineris-00970622v1

The in vitro blood-testis-barrier : a new promising alternative for reproductive toxicity studies

Audrey Legendre , Sophie Desmots , Anthony Lecomte , Pascal Froment , René Habert , et al.
1. European Doctoral College on Environment and Health (EDCEH), Jun 2010, Rennes, France
Conference papers ineris-00970640v1

Elaboration d'un modèle toxicocinétique de la cis et trans-perméthrine et de ses métabolites chez le rat

Marie-Emilie Willemin , Sophie Desmots , Rozenn Le Grand , Florence Anna Zeman , François Lestremau , et al.
5. journées internationales de toxicologie, Oct 2013, Liège, Belgium
Conference papers ineris-00971203v1
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Mise en place d'une barrière hémato-testiculaire in vitro comme méthode alternative et complémentaire à l'expérimentation animale pour l'étude des effets des perturbateurs de la fonction endocrinienne

Audrey Legendre , Sophie Desmots , Anthony Lecomte , Franck Robidel , Olivier Dupont , et al.
25. Congrès de la Société d'Andrologie de Langue Française (SALF 2008), Sep 2008, Hammamet, Maroc
Conference poster ineris-00970396v1

Endocrine disruption and steroidogenesis : integrated evaluation from gonadal steroidogenic enzymes in vitro and in vivo to hormonal balance and fertility assessment in vivo

Nadia Quignot , Sophie Desmots , Robert Barouki , Emmanuel Lemazurier
8. World Congress on Alternatives and Animal Use in the Life Sciences, Aug 2011, Montreal, Canada
Conference papers ineris-00970887v1

Development of alternative to animal methods for reproductive toxicity studies : An in vitro blood - testis - barrier

Audrey Legendre , Sophie Desmots , Anthony Lecomte , Franck Robidel , Olivier Dupont , et al.
7. World congress on alternatives and animal use in the life sciences, Aug 2009, Rome, Italy
Conference papers ineris-00970502v1

Transcriptional signature of human macrophages exposed to the environmental contaminant benzo(a)pyrene.

Lydie Sparfel , Marie-Laure Pinel-Marie , Magali Boize , Serge Koscielny , Sophie Desmots , et al.
Toxicological Sciences, 2010, 114 (2), pp.247-59. ⟨10.1093/toxsci/kfq007⟩
Journal articles istex hal-00657921v1

Aryl hydrocarbon receptor-dependent induction of the IgA receptor FcalphaRI by the environmental contaminant benzo(a)pyrene in human macrophages

Lydie Sparfel , Marie-Laure Pinel-Marie , L. Louarn , Sophie Desmots , Olivier Fardel
47. European Congress of Toxicology (EUROTOX 2011), Aug 2011, Paris, France
Conference papers ineris-00970856v1
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Prediction of dose-hepatotoxic response in humans based on toxicokinetic/toxicodynamic modeling with or without in vivo data : A case study with acetaminophen

Alexandre R.R. Pery , Céline Brochot , Florence Anna Zeman , Enrico Mombelli , Sophie Desmots , et al.
Toxicology Letters, 2013, 220 (1), pp.26-34. ⟨10.1016/j.toxlet.2013.03.032⟩
Journal articles ineris-00961804v1

Intérêt potentiel de cibles géniques des hydrocarbures aromatiques polycycliques en tant que biomarqueurs d'exposition

Lydie Sparfel , Marie-Laure Pinel-Marie , Serge Koscielny , Sophie Desmots , Alexandre R.R. Pery , et al.
Environnement, Risques & Santé, 2011, 10 (3), pp.195-199
Journal articles hal-00682429v1

Identification de nouveaux gènes cibles des hydrocarbures aromatiques polycycliques dans les macrophages humains en culture primaire par une approche transcriptomique

Lydie Sparfel , Marie-Laure Pinel-Marie , Magali Boize , Serge Koscielny , Sophie Desmots , et al.
Congrès de la Société de Pharmaco-Toxicologie Cellulaire " Toxicologie prédictive : les voies du futur ", May 2010, Paris, France
Conference papers hal-00674292v1

Apports des approches " omiques " pour modéliser la cinétique et les effets de xénobiotiques chez l'homme

Alexandre R.R. Pery , Céline Brochot , M. Dumas , Magali Boize , Sophie Desmots , et al.
Colloque ARET, Jun 2010, Paris, France
Conference papers hal-00674296v1

Effects of endocrine disruptors in adult rats: integrative evaluation from gonadal steroidogenic gene expression profiles to hormonal balance

Nadia Quignot , Sophie Desmots , Robert Barouki , Emmanuel Lemazurier
Society for Endocrinology BES 2011 meeting, Apr 2011, Birmingham, United Kingdom
Conference papers ineris-00970765v1

Aryl hydrocarbon receptor-dependent induction of the IgA receptor FcαRI by the environmental contaminant benzo(a)pyrene in human macrophages.

Marie-Laure Pinel-Marie , Laetitia Louarn , Sophie Desmots , Olivier Fardel , Lydie Sparfel
Toxicology, 2011, 290 (1), pp.89-95. ⟨10.1016/j.tox.2011.08.018⟩
Journal articles istex hal-00682119v1
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Determination of cis-permethrin, trans-permethrin and associated metabolites in rat blood and organs by gas chromatography–ion trap mass spectrometry

Francois Lestremau , Marie-Emilie Willemin , Claudine Chatellier , Sophie Desmots , Céline Brochot
Analytical and Bioanalytical Chemistry, 2014, 406 (14), pp.3477-3487. ⟨10.1007/s00216-014-7774-z⟩
Journal articles ineris-01710209v1

Aryl hydrocarbon receptor-dependent induction of the NADPH oxidase subunit NCF1/p47 phox expression leading to priming of human macrophage oxidative burst.

Marie-Laure Pinel-Marie , Lydie Sparfel , Sophie Desmots , Olivier Fardel
Free Radical Biology and Medicine, 2009, 47 (6), pp.825-34. ⟨10.1016/j.freeradbiomed.2009.06.025⟩
Journal articles istex hal-00673349v1
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Self-reported parental exposure to pesticide during pregnancy and birth outcomes : The MecoExpo cohort study

Flora Mayhoub , Thierry Berton , Véronique Bach , Karine Tack , Caroline Deguines , et al.
PLoS ONE, 2014, 9 (6), pp.e99090. ⟨10.1371/journal.pone.0099090⟩
Journal articles ineris-01862439v1

Changes in cellular localization of claudin-11 and P-glycoprotein during rat testis development

Audrey Legendre , Sophie Desmots , Anthony Lecomte , Franck Robidel , Olivier Dupont , et al.
16. European Workshop on Molecular and Cellular Endocrinology of the Testis (European Testis Workshop; ETW16), May 2010, La Biodola, Italy
Conference papers ineris-00970643v1