Evaluation of estrogenic activities of benzophenone derivatives using new in vitro and in vivo zebrafish models
François Brion
,
Anne Cosnefroy
,
Nathalie Hinfray
,
Benjamin Piccini
,
Patrick Balaguer
,
et al.
1. European Conference on the Replacement, Reduction and Refinement of Animal Experiments in Ecotoxicology , Jun 2012, Dübendorf, Switzerland
Conference papers
ineris-00971019v1
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New transgenic zebrafish models to study the expression of key steroidgenic enzymes and their perturbation by endocrine disrupting chemicals
Nathalie Hinfray
,
Morgane Caulier
,
Yann Guiguen
,
Olivier Kah
,
Benjamin Piccini
,
et al.
24. SETAC Europe annual meeting "Science across bridges, borders and boundaries" , May 2014, Bâle, Switzerland. pp.251
Conference papers
ineris-01855504v1
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Assessment of the estrogenic potency of chemicals, alone or in combination, and complex environmental mixtures using a novel transgenic cy19a1b-GFP in vivo zebrafish assay (EASZY assay)
François Brion
,
Nathalie Hinfray
,
Nicolas Creusot
,
Olivier Kah
,
Jean-Marc Porcher
,
et al.
24. SETAC Europe annual meeting "Science across bridges, borders and boundaries" , May 2014, Bâle, Switzerland. pp.64
Conference papers
ineris-01862419v1
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New transgenic zebrafish models to study the expression of key steroidogenic enzymes and their perturbation by endocrine disrupting chemicals
Nathalie Hinfray
,
Morgane Caulier
,
Yann Guiguen
,
Olivier Kah
,
Benjamin Piccini
,
et al.
27. Conference of European Comparative Endocrinologists (CECE 2014) , Aug 2014, Rennes, France
Conference papers
ineris-01852880v1
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Integrated approaches to investigate the effect of progestins in fish and their occurrence in the aquatic environment
François Brion
,
Selim Ait-Aissa
,
Olivier Kah
,
Patrick Balaguer
,
Hélène Budzinski
NORMAN Workshop "Integrated Exposure and Effects Assessment" , Apr 2017, Amsterdam, Netherlands
Conference papers
ineris-01853437v1
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Transgenic (cyp19a1b-GFP) zebrafish embryos as a tool for assessing combined effects of oestrogenic chemicals.
Karina Petersen
,
Eva Fetter
,
Olivier Kah
,
François Brion
,
Stefan Scholz
,
et al.
Journal articles
hal-00877351v1
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Aromatase B is expressed in progenitor cells in the brain of adult zebrafish
Karen Mouriec
,
Elisabeth Pellegrini
,
F. Brion
,
Isabelle Anglade
,
Farzad Pakdel
,
et al.
8th International Symposium on Reproductive Physiology of Fish , Jun 2007, Saint Malo, France. pp.28-30
Conference papers
hal-00180597v1
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Aromatase in the brain of teleost fish: expression, regulation and putative functions.
Nicolas Diotel
,
Yann Le Page
,
Karen Mouriec
,
Sok-Keng Tong
,
Elisabeth Pellegrini
,
et al.
Journal articles
hal-00472008v1
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Effect of (xeno)-estrogens on zebrafish P450c17 (C17, 17 alpha-hydroxylase/17, 20-lyase) mRNA and protein expression in gonadal tissue.
F. Brion
,
N. Hinfray
,
O. Palluel
,
Julien Maillard
,
Isabelle Anglade
,
et al.
8th International Symposium on Reproductive Physiology of Fish , Jun 2007, Saint-Malo, France. pp.245-246
Conference papers
hal-00450197v1
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The xeno-estrogen 4-nonylphenol affects brain and ovarian aromatase expression in the zebrafish
Nathalie Hinfray
,
Olivier Palluel
,
Jean-Marc Porcher
,
Olivier Kah
,
Farzad Pakdel
,
et al.
2. International Conference "Molecular research in environmental medecine" , Sep 2006, Paris, France
Conference papers
ineris-00970105v1
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17alpha-ethinylestradiol disrupts the ontogeny of the forebrain GnRH system and the expression of brain aromatase during early development of zebrafish.
Mélanie Vosges
,
Yann Le Page
,
Bon-Chu Chung
,
Yves Combarnous
,
Jean-Marc Porcher
,
et al.
Journal articles
istex
hal-00592402v1
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Expression of zebra fish aromatase cyp19a and cyp19b genes in response to the ligands of estrogen receptor and aryl hydrocarbon receptor.
Ksenia Cheshenko
,
Francois Brion
,
Yann Le Page
,
Nathalie Hinfray
,
Farzad Pakdel
,
et al.
Journal articles
hal-00140538v1
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Development and validation of an OECD test guideline incorporating a transgenic fish model
François Brion
,
Benjamin Piccini
,
Cyril Turies
,
Jean-Marc Porcher
,
J. Green
,
et al.
25. SETAC Europe annual meeting , May 2015, Barcelone, Spain. pp.52
Conference papers
ineris-01852936v1
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Inhibitory effect of cadmium on estrogen signaling in zebrafish brain and protection by zinc
Lina Chouchene
,
Elisabeth Pellegrini
,
Marie-Madeleine Gueguen
,
Nathalie Hinfray
,
François Brion
,
et al.
Journal articles
hal-01274217v1
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New transgenic zebrafish models to study the expression of key steroidogenic enzymes and their perturbation by endocrine disrupting chemicals
Nathalie Hinfray
,
Morgane Caulier
,
Yann Guiguen
,
Olivier Kah
,
B. Piccini
,
et al.
27. Conference of European Comparative Endocrinologists , Aug 2014, Rennes, France. 2014, CECE 2014
Conference poster
hal-02743760v1
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Interference between estrogen (ER) and aryl hydrocarbon receptors (AhR) signalling pathways in two fish models: the PELN cell line and zebrafish embryos.
S. Ait-Aissa
,
A. Cosnefroy
,
D. Baudiffier
,
F. Brion
,
Olivier Kah
,
et al.
15th International Congress on In Vitro Toxicology , Sep 2008, Stokholm, Sweden
Conference papers
hal-00450232v1
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The zebrafish cyp19a1b gene : regulation and application to the endocrine disruption study
Yann Le Page
,
François Brion
,
Sok-Keng Tong
,
Farzad Pakdel
,
Bon-Chu Chung
,
et al.
1. International Symposium on Neuroendocrine Effects of Endocrine Disruptors (NEED Symposium) , Jul 2010, Rouen, France
Conference papers
ineris-00970656v1
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A highly sensitive in vivo assay for the detection of estrogenic activity using tg(cyp19a1b-GFP) transgenic zebrafish embryos
François Brion
,
Benjamin Piccini
,
Yann Le Page
,
Bon-Chu Chung
,
Selim Ait-Aissa
,
et al.
16. Symposium on Pollutant Responses in Marine Organisms (PRIMO 16) , May 2011, Long Beach, United States
Conference papers
ineris-00970768v1
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Screening estrogenic activity using tg(cyp19a1b-GFP) transgenic zebrafish embryos
Olivier Kah
,
François Brion
1. European Conference on the Replacement, Reduction and Refinement of Animal Experiments in Ecotoxicology , Jun 2012, Dübendorf, Switzerland
Conference papers
ineris-00971017v1
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Effect of (xeno)-estrogens on zebrafish P450c17 (C17, 17 alpha-hydroxylase/17, 20-lyase) mRNA and protein expression in gonadal tissue
François Brion
,
Nathalie Hinfray
,
Olivier Palluel
,
Julien Maillard
,
Isabelle Anglade
,
et al.
Cybium : Revue Internationale d’Ichtyologie , 2008, 32 (2, suppl. S), pp.245-246
Journal articles
ineris-00963150v1
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Neuroendocrine disruption in aquatic species: recent data in zebrafish
Olivier Kah
,
Yann Le Page
,
Mélanie Vosges
,
Sok-Keng Tong
,
Jean Marc Porcher
,
et al.
IPSEN Conference on Multi-System Endocrine Disruption , Nov 2010, Paris, France
Conference papers
hal-00666899v1
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Screening of the estrogenic activity of environmental samples using transgenic cyp19a1b-GFP zebrafish embryos
E. Fetter
,
S. Scholz
,
M. Krauss
,
Werner Brack
,
K. Petersen
,
et al.
6. SETAC World Congress 2012 / 22. SETAC Europe Annual Meeting "Securing a sustainable future : integrating science, policy and people" , May 2012, Berlin, Germany
Conference papers
ineris-00970972v1
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Aromatase, oestrogènes et plasticité cérébrale chez les poissons
Olivier Kah
,
Elisabeth Pellegrini
,
Karen Mouriec
,
Arnaud Menuet
,
Isabelle Anglade
,
et al.
2. Colloque méditerranéen de neurosciences , Dec 2006, Marrakech, Maroc
Conference papers
ineris-00970147v1
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A novel in vivo assay to assess the estrogenic activity of chemical substances using transgenic cyp19a1b-GFP zebrafish embryos
François Brion
,
Benjamin Piccini
,
Yann Le Page
,
Sok-Keng Tong
,
Jean-Marc Porcher
,
et al.
International Workshop "The zebrafish embryo model in toxicology and teratology" , Sep 2010, Karlsruhe, Germany
Conference papers
ineris-00970671v1
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Screening Estrogenic Activities of Chemicals or Mixtures In Vivo Using Transgenic (cyp19a1b-GFP) Zebrafish Embryos
François Brion
,
Yann Le Page
,
Benjamin Piccini
,
Olivier Cardoso
,
Sok-Keng Tong
,
et al.
Journal articles
hal-00877371v1
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Neurodevelopmental effects of natural and synthetic ligands of estrogen and progesterone receptors in zebrafish eleutheroembryos
Olivier Kah
,
François Brion
,
Elisabeth Pellegrini
,
Colette Vaillant
,
Marie-Madeleine Gueguen
,
et al.
Journal articles
hal-02441213v1
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Effects of ethinylestradiol on ontogenesis of GnRH neurons during zebrafish development.
M. Vosges
,
Yann Le Page
,
Ming-Wei Kuo
,
B. C. Chung
,
Jm Porcher
,
et al.
13th Annual Meeting of the LARC Neuroscience network , Oct 2009, Caen, France
Conference papers
hal-00450681v1
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Oestrogens and neurogenesis: new functions for an old hormone. Lessons from the zebrafish.
Olivier Kah
,
Elisabeth Pellegrini
,
Karen Mouriec
,
Nicolas Diotel
,
Isabelle Anglade
,
et al.
Journal articles
istex
hal-00379272v1
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Évaluation des effets endocrines des œstrogènes mimétiques et des composés à activité dioxine sur l'expression de gènes cibles et impacts fonctionnels sur la reproduction chez le poisson
François Brion
,
Nathalie Hinfray
,
Jean-Marc Porcher
,
Farzad Pakdel
,
Olivier Kah
Colloque national PNRPE, Recherche sur les Perturbateurs endocriniens , Mar 2008, Angers, France
Conference papers
hal-00675627v1
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How adult fish grow their brains ? A functional link between neurogenesis and aromatase activity in zebrafish
Elisabeth Pellegrini
,
Karen Mouriec
,
Arnaud Menuet
,
Isabelle Anglade
,
François Brion
,
et al.
23. Conference of European comparative endocrinologists , Sep 2006, Manchester, United Kingdom
Conference papers
ineris-00970103v1
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