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Communication Dans Un Congrès Année : 2024

Short-term effects of ultrafine particles on mortality

Ioar Rivas
  • Fonction : Auteur
Meritxell Garcia-Marles
  • Fonction : Auteur
Marjan Savadkoohi
  • Fonction : Auteur
Marco Pandolfi
  • Fonction : Auteur
Andres Alaustey
  • Fonction : Auteur
Panayiotis Kalkavouras
  • Fonction : Auteur
Nikos Mihalopoulos
  • Fonction : Auteur
Georgios Grivas
  • Fonction : Auteur
Cristina Reche
  • Fonction : Auteur
Noemi Perez
  • Fonction : Auteur
Xiansheng Liu
  • Fonction : Auteur
Imre Salma
  • Fonction : Auteur
Mate Vörösmarty
  • Fonction : Auteur
Andrea Casans
  • Fonction : Auteur
Juan Andres Casquero-Vera
  • Fonction : Auteur
Tuukka Petäjä
  • Fonction : Auteur
Janne Lampilahti
  • Fonction : Auteur
Hilkka Timonen
  • Fonction : Auteur
Kay Weinhold
  • Fonction : Auteur
Alfred Wiedensohler
  • Fonction : Auteur
Dimitris Evangelopoulos
  • Fonction : Auteur
Anja H. Tremper
  • Fonction : Auteur
David C. Green
  • Fonction : Auteur
Francisco J. Gomez-Moreno
  • Fonction : Auteur
Elisabeth Alonso-Blanco
  • Fonction : Auteur
Christoph Hueglin
  • Fonction : Auteur
Jean-Eudes Petit
  • Fonction : Auteur
Hicran Altug
  • Fonction : Auteur
Barbara Hofmann
  • Fonction : Auteur
Joan Ballester
  • Fonction : Auteur
Anouk Marsal
  • Fonction : Auteur
Gaëlle Uzu
  • Fonction : Auteur
Valerie Siroux
  • Fonction : Auteur
Karine Supernant
  • Fonction : Auteur
Roy M. Harrison
  • Fonction : Auteur
Gerard Hoek
  • Fonction : Auteur
Xavier Basagaña
  • Fonction : Auteur
Xavier Querol
  • Fonction : Auteur

Résumé

Particulate matter (PM) was estimated to cause 4.2 million deaths worldwide in 2019; however, evidence on which components are responsible for its effects on mortality remains inconsistent. Ultrafine particles (UFP, < 100 nm in diameter), the smallest fractions of PM, have the potential to individually harm health as they are small enough to reach multiple organs of the human body in contrast to larger fractions. To efficiently decrease the effects of PM on health, it is crucial to understand which PM components pose the highest health risks and to tackle them in future regulations. In this study, we aim to quantify the short-term effects of PM properties and components on mortality from natural, cardiovascular and respiratory causes. We associated daily concentrations of different PM properties and components (including UFP size fractions, UFP sources, black carbon, lung deposition surface area, PM2.5 (<2.5µm) and PM10 (<10µm)) with daily counts of mortality from 12 EU cities using quasi-Poisson single and multi-pollutant regression models (Generalized non-linear model framework). The models were adjusted for seasonal and long-term trends, temperature (cold and warm days), relative humidity, bank holidays and day of the week. The effects of lagged exposure (0-7 days) and lagged temperature were also evaluated. To minimize the impact of different analytical methodologies, measurements were conducted following a standardised protocol in all cities, particles were size classified consistently, and all the data was treated by the same research team. A random effect meta-analysis was carried out to average the effects across all EU cities. The preliminary results reported here focus on the health effects of different particle size fractions and are based on seven cities (Athens, Barcelona, Budapest, Granada, Helsinki, Madrid and Zurich). The remaining cities will be analysed in situ and included in the meta-analysis soon. Our meta-analysis of single pollutant models suggests that nearly all particle size modes (e.g., nucleation (10-25 nm), Aitken (25-100nm), UFP (<100nm), Ntotal (>10nm) and N25 (>25 nm) are associated with significant increases in relative risk (RR) of natural and cardiovascular disease mortality, at lags 0 to 3. For example, an interquartile range increase in UFP (IQR: 3804 particles/cm3) was associated with a 0.8% [95% confidence interval: 0.2%, 1.5%] increase in natural mortality and 1% (95% confidence interval: 0.2%, 1.8%) in cardiovascular mortality. A significant risk of cardiovascular mortality was also observed 4-6 days after exposure to most particle size modes. We did not find significant associations between particle modes and respiratory mortality. The Nucleation, Aitken, UFP and Ntotal (>10 nm) modes showed similar results, indicating that both UFP and Ntotal (>10 nm) could potentially be used as indicators for the health effects of the smallest aerosol size fractions, dominant in number. The health effects of the UFP mode remained statistically significant for natural mortality after adjusting for PM2.5. Similarly, the effects of the UFP mode remained significant for natural and cardiovascular mortality after individually adjusting for PM10 and NO2. Our preliminary results suggest that the smallest aerosol particle size fractions (e.g., UFP) may independently impact health.
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Dates et versions

ineris-04555203 , version 1 (22-04-2024)

Identifiants

Citer

Vanessa N. dos Santos, Ioar Rivas, Meritxell Garcia-Marles, Marjan Savadkoohi, Marco Pandolfi, et al.. Short-term effects of ultrafine particles on mortality. EGU General Assembly 2024, Apr 2024, Vienne (AUT), France. ⟨10.5194/egusphere-egu24-11346⟩. ⟨ineris-04555203⟩

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