%0 Journal Article %T GFAP expression in the rat brain following sub-chronic exposure to a 900 MHz electromagnetic field signal %+ Institut National de l'Environnement Industriel et des Risques (INERIS) %+ Laboratoire de Physiologie Intégrée %A Ammari, Mohamed %A Gamez, Christelle %A Lecomte, Anthony %A Sakly, Mohsen %A Abdelmelek, Hafedh %A de Seze, René %< avec comité de lecture %@ 0955-3002 %J International Journal of Radiation Biology %I Taylor and Francis %V 86 %N 5 %P 367-375 %8 2010 %D 2010 %R 10.3109/09553000903567946 %M 20397841 %K ASTROCYTE %K GLIAL FIBRILLARY ACIDIC PROTEIN (GFAP) %K ELECTROMAGNETIC FIELD %K RAT %K BRAIN %Z Life Sciences [q-bio]/Toxicology %Z Environmental SciencesJournal articles %X Methods: Sprague-Dawley rats were exposed for 45 min/day at a brain-averaged specific absorption rate (SAR) = 1.5 W/kg or 15 min/day at a SAR = 6 W/kg for five days per week during an eight-week period. GFAP expression was measured by the immunocytochemistry method in the following rat brain areas: Prefrontal cortex, cerebellar cortex, dentate gyrus of the hippocampus, lateral globus pallidus of the striatum, and the caudate putamen. Results: Compared to the sham-treated rats, those exposed to the sub-chronic GSM (Global System for mobile communications) signal at 1.5 or 6 W/kg showed an increase in GFAP levels in the different brain areas, three and ten days after treatment. Conclusion: Our results show that sub-chronic exposures to a 900 MHz EMF signal for two months could adversely affect rat brain (sign of a potential gliosis). %G English %L ineris-00963219 %U https://ineris.hal.science/ineris-00963219 %~ SDE %~ INERIS %~ GIP-BE